This caricature of José Saramago (Nobel Prize in Literature) is one of my favorites. It's inspired on one of his greatest books, "Stone Raft", and it was made in Photoshop only with the mouse. I had to create a lot of layers – every detail is, lets say, independent: each eye, nose, mouth, ears, face, neck and so one...
This caricature was the cover of the portuguese version of Advanced Photoshop's magazine.